Utilities of these focused on knowing how the genome varies between individuals and populations, and knowing which regions are functional. In this sense, although it is known that only a small percentage of the sequence corresponds to genes, there are innumerable functional regions. They perform the important role of regulating gene expression or cellular processes. Thus, the term “ junk dna ” is increasingly questioned. And it is that, in science, we cannot consider that something “is there to be”.
New genome sequencing techniques despite the fact that the first sequencing of the genome marked a before and after in terms of therapeutic possibilities, a fax number list not insignificant 8% of the genome was missing (if each of our cells contains about three billion bases, 8% represents about 200 millions, comparable in size to an entire chromosome). The complexity of some areas the inability to "read" these areas of dna is that they are extremely complex because they are highly variable and repetitive places. These terms seem mutually exclusive.
However, we must understand that there are places in the genome that are repeated countless times but that each repetition is different. Thus, in both telomeres and centromeres , there are repeats that vary in length, type, and position. Why couldn't these crucial areas be sequenced? For the simple reason that genome sequencing methods to date only allowed short sequences to be assembled (several hundred or a few thousand bases). Thus, trying to order and make sense of the 200 million bases (remember, highly repetitive