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Unfortunately, keto diets are probably more prone than many others to end with weight regain because they can be hard to stick to in the long run, Carson said. And being in ketosis for more than a few weeks might not be best for overall health, she said. That's true of many diet studies, the researchers noted, so study results likely look rosier than weight loss in the real world. For reasons not entirely understood even today, fueling the body on primarily ketones reduces seizures.